Thank you for this post and for letting me to pick your brain.
The most important feature for me now is auto completion(keyboard shortcuts will be nice later) ... coz beginner here
I played a few days with r in the past and i stopped using it coz excel solved my problem
You mention that "has problems by handling big data sets" .... that was my problem with excel ... data from 10 days was the maximum threshold
What do you recommend for big datasets? a db? another language or software?
What wold be your approach if you need to work with "big data" ?
Thank you for Maindonald book i will start with it(coz ... the license ):
Also Docker containers for Bioconductor seems interesting; do you have any experience with this? how memory intesnive are the containers?